Potential Side effects of Semaglutide

Semaglutide is a widely used medication for weight loss (Wegovy) and type 2 diabetes mellitus (Ozempic), but like any medication, it has potential side effects that should be considered. Understanding the potential side effects of semaglutide (Ozempic, Wegovy) is important in making informed decisions about treatment options.

Common side effects of semaglutide use include nausea, vomiting, diarrhea, constipation, abdominal pain, headache, fatigue, and dizziness. These side effects can often be managed with dosage adjustments or other medications. However, less common but serious side effects may require immediate medical attention.

Common Potential Side Effects of Semaglutide

  • Nausea (20-30%)
  • Vomiting (10-20%)
  • Diarrhea (10-20%)
  • Constipation (10-20%)
  • Abdominal pain (5-15%)
  • Headache (10-15%)
  • Fatigue (5-10%)
  • Dizziness (5-10%)

For more information visit the Ozempic website

Potential Serious Side Effects of Semaglutide

These serious side effects include acute pancreatitis, diabetic retinopathy, kidney problems, hypoglycemia, gallbladder disease, and thyroid cancer. Diabetic retinopathy and kidney problems are of particular concern, as they are both common complications of diabetes and may be exacerbated by semaglutide use.


  • Acute Pancreatitis (less than 1%)
  • Diabetic Retinopathy (less than 1%)
  • Kidney Problems (less than 1%)
  • Hypoglycemia (less than 1%)
  • Gallbladder Disease (less than 1%)
  • Thyroid Cancer (unclear, but it is a rare side effect that has been reported in some patients)

Please note that these percentages are approximate and can vary depending on individual factors such as age, weight, and medical history. It is important to discuss any concerns or potential side effects with a healthcare provider.

Check out this post by the MayoClinic for more information

In conclusion, while semaglutide is an effective treatment option for both weight loss and type 2 diabetes mellitus, it is important to be aware of the potential side effects of semaglutide (Ozempic, Wegovy) associated with its use. By understanding these potential side effects and working closely with their healthcare provider, patients can safely and effectively manage their weight and diabetes.

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