Advanced Minimally Invasive Weight Loss Solutions from a Johns Hopkins-Trained Bariatric Expert
Advanced Minimally Invasive Weight Loss Solutions from a Johns Hopkins-Trained Bariatric Expert
At Lalezari Surgical in Los Angeles, Dr. Sepehr Lalezari, MD, FACS, leverages his fellowship training from Johns Hopkins Medicine and eight years of specialized bariatric expertise to offer a comprehensive variety of procedural weight loss options designed to provide effective, minimally invasive alternatives to traditional surgical methods. As a board-certified bariatric surgeon with published research in minimally invasive techniques and recognition as a Los Angeles Magazine “Top Doctor” (2021-2024), Dr. Lalezari combines his surgical expertise with advanced endoscopic procedures to deliver optimal patient outcomes.
These innovative procedures are ideal for individuals seeking significant weight loss without the need for major surgery, offering shorter recovery times, lower risks, and often reversible solutions. Dr. Lalezari’s unique perspective as both a skilled endoscopist and experienced bariatric surgeon ensures that patients receive the most appropriate treatment for their individual circumstances, with seamless access to surgical options if needed.

Our Advanced Solutions for Procedural Weight Loss
- Gastric Balloon
The Gastric Balloon involves placing a saline-filled silicone balloon in the stomach to occupy space, creating a feeling of fullness and reducing food intake. Dr. Lalezari’s extensive endoscopic experience ensures safe and effective balloon placement and removal. This procedure is performed endoscopically through the mouth under conscious sedation, and the balloon remains in the stomach for about six months before being removed.
Available Balloon Systems:
- Orbera Balloon: Single balloon system with proven track record
- Obalon Balloon System: Multiple gas-filled balloons placed sequentially
- Spatz3 Adjustable Balloon: Unique adjustable volume capability for personalized treatment
Expected Outcomes: Patients typically lose 20-30% of excess body weight during the six-month treatment period. Dr. Lalezari’s comprehensive support program maximizes weight loss potential and helps establish long-term healthy habits.
- Endoscopic Sleeve Gastroplasty (ESG) — EndoSleeve
Also known as the “accordion procedure,” ESG reduces the size of the stomach using sutures, leveraging Dr. Lalezari’s advanced endoscopic suturing expertise. An endoscope is inserted through the mouth into the stomach, and a specialized suturing device is used to fold and stitch the stomach, reducing its volume by approximately 70%. This procedure mimics the effects of Dr. Lalezari’s surgical sleeve gastrectomy but is less invasive and potentially reversible.
Procedure Advantages:
- No external incisions required
- Same-day discharge capability
- Preserves normal anatomy
- Can be converted to surgical options if needed
Expected Results: Patients typically achieve 15-20% total body weight loss over 12-18 months, comparable to surgical sleeve gastrectomy in appropriate candidates.
- AspireAssist
AspireAssist is an innovative device that allows patients to remove a portion of food from their stomach after eating. Dr. Lalezari’s surgical expertise ensures optimal tube placement through the abdominal wall, connected to a small port on the outside of the abdomen. After meals, patients can drain approximately 30% of stomach contents through the tube, reducing calorie absorption. This method is non-surgical, reversible, and adjustable based on patient needs.
Key Features:
- Minimally invasive tube placement
- Patient-controlled calorie reduction
- Completely reversible
- Lifestyle-based approach to weight loss
Clinical Outcomes: Studies show 12-15% total body weight loss over one year when combined with lifestyle counseling.
- Transoral Outlet Reduction (TORe)
Transoral Outlet Reduction (TORe) is a specialized procedure for patients who have regained weight after gastric bypass surgery. Dr. Lalezari’s extensive experience with both primary and revisional bariatric surgery makes him uniquely qualified to perform this advanced endoscopic revision. The procedure reduces the size of the gastric pouch outlet by suturing to decrease its diameter, slowing food passage and promoting satiety.
Ideal Candidates:
- Previous gastric bypass patients with weight regain
- Enlarged gastro-jejunal anastomosis
- Desire to avoid revisional surgery
Expected Outcomes: Patients typically experience renewed satiety and 15-20% additional excess weight loss following TORe.
- Intragastric Botox Injections
Intragastric Botox Injections involve injecting Botox (botulinum toxin) into specific stomach muscles to relax them, slowing gastric emptying and reducing appetite. Dr. Lalezari uses endoscopic guidance to precisely inject Botox into targeted areas of the stomach antrum and fundus. This method is non-surgical, minimally invasive, and temporary, with effects lasting 3-6 months.
Treatment Protocol:
- Outpatient endoscopic procedure
- Multiple injection sites for optimal coverage
- Can be repeated as needed
- Minimal recovery time required
Clinical Benefits: Studies show 10-15% body weight reduction over 3-6 months, making it ideal for patients requiring temporary assistance with portion control.
- Plenity
Plenity is an FDA-approved weight management product that offers a non-systemic, non-pharmacological approach to weight loss. Composed of naturally derived, absorbent hydrogel particles made from cellulose and citric acid, Plenity comes in the form of capsules taken orally. When taken with water before meals, the hydrogel particles expand in the stomach and small intestine, creating a sensation of fullness and helping to reduce food intake.
Mechanism of Action:
- Expands to create volume in the digestive tract
- No systemic absorption or metabolism
- Eliminates naturally through the digestive system
- No drug interactions or contraindications
Clinical Results: FDA approval was based on studies showing 6.4% total body weight loss compared to 4.4% with placebo over 24 weeks.
Advanced Endoscopic Revision Procedures
- Endoscopic Gastric Bypass Revision
For patients with previous gastric bypass experiencing complications or inadequate weight loss, Dr. Lalezari offers endoscopic revision options including:
- Pouch reduction techniques
- Outlet size optimization
- Stricture management
- Marginal ulcer treatment
- Post-Surgical Optimization
Dr. Lalezari’s surgical background allows him to optimize outcomes for patients with previous bariatric surgery through:
- Endoscopic pouch remodeling
- Anatomical restoration procedures
- Complication management
- Weight regain prevention strategies
Benefits of Procedural Weight Loss Under Expert Care
- Minimally Invasive with Expert Precision
These procedures typically involve significantly less risk and shorter recovery times compared to traditional surgeries, while benefiting from Dr. Lalezari’s surgical precision and endoscopic expertise.
- Reversible and Adjustable Options
Many of these options are reversible or adjustable, providing flexibility for patients who may require different approaches over time. Dr. Lalezari’s comprehensive understanding of all weight loss options ensures optimal treatment selection.
- Effective Weight Loss with Professional Support
Patients can achieve significant weight loss and improvements in obesity-related conditions under the care of a fellowship-trained specialist with extensive experience in weight loss outcomes.
- Lower Risk Profile with Surgical Backup
With no major surgery involved, the risk of complications is significantly minimized, while having access to surgical options if needed provides additional confidence and flexibility.
- Evidence-Based Approach
Dr. Lalezari’s published research and continuing medical education ensure that all procedures reflect current best practices and optimal patient selection criteria.
Is Procedural Weight Loss Right for You?
Candidates for procedural weight loss under Dr. Lalezari’s care typically include individuals who:
- Clinical Criteria
- Have a Body Mass Index (BMI) of 30 or higher
- Have struggled with weight loss through diet and exercise alone
- Are looking for non-surgical options to achieve significant weight loss
- Prefer procedures with minimal risk and recovery time
- Want expert care from a fellowship-trained bariatric specialist
- Ideal Patient Characteristics
- Motivated to make lifestyle changes
- Realistic expectations about weight loss outcomes
- Commitment to follow-up care and monitoring
- Understanding that results require patient participation
- Interest in potentially transitioning to surgical options if needed
- Medical Considerations
- Absence of contraindications to endoscopic procedures
- Stable medical conditions
- No active substance abuse or uncontrolled psychiatric conditions
- Ability to comply with post-procedure dietary guidelines

The Lalezari Surgical Advantage
- Fellowship-Trained Expertise
Dr. Lalezari’s Johns Hopkins training in minimally invasive techniques provides patients with access to the most advanced endoscopic procedures available, performed with surgical precision.
- Comprehensive Treatment Options
Unlike single-modality providers, Dr. Lalezari offers the complete spectrum of weight loss options, from medical management through advanced surgical procedures, ensuring optimal treatment selection.
- Research-Based Protocols
Dr. Lalezari’s published research in minimally invasive bariatric techniques ensures that patients receive evidence-based care reflecting the latest advances in the field.
- Seamless Transition Capability
Patients who require more intensive intervention can seamlessly transition to surgical options under the same expert care, maintaining continuity of treatment and physician relationship.
- Multidisciplinary Support
Dr. Lalezari’s practice includes registered dietitians, psychologists, and specialized nursing staff to provide comprehensive support throughout the weight loss journey.
What to Expect During Your Treatment
Initial Consultation and Evaluation
Dr. Lalezari personally conducts a comprehensive evaluation including:
- Detailed medical history and physical examination
- Review of previous weight loss attempts
- Assessment of psychological readiness
- Discussion of all available treatment options
- Development of personalized treatment plan
Procedure Preparation
- Pre-procedure medical clearance
- Nutritional counseling and dietary preparation
- Psychological evaluation if indicated
- Insurance verification and financial counseling
- Detailed procedure explanation and consent
Procedure Day Experience
- Outpatient setting with state-of-the-art equipment
- Conscious sedation for patient comfort
- Minimally invasive approach with expert technique
- Same-day discharge for most procedures
- Comprehensive discharge instructions and support
Post-Procedure Care and Follow-up
- Regular follow-up appointments with Dr. Lalezari
- Nutritional counseling and meal planning
- Behavioral modification support
- Weight and health monitoring
- Long-term maintenance planning
Frequently Asked Questions About Non-Surgical Weight Loss
Dr. Lalezari's comprehensive evaluation considers your medical history, weight loss goals, lifestyle factors, and personal preferences to recommend the most appropriate procedure for your individual circumstances.
Coverage varies by insurance provider and specific procedure. Our insurance specialists work with your provider to maximize coverage and provide transparent cost information.
Dr. Lalezari's expertise allows for seamless evaluation of surgical options if non-surgical approaches are insufficient, ensuring you always have access to more intensive treatments.
Weight loss varies by procedure type and individual factors, typically ranging from 10-30% total body weight loss depending on the specific treatment and patient compliance.
While significantly lower than surgical risks, all procedures carry some risk. Dr. Lalezari's extensive training and experience minimize complications while maximizing safety.
Some procedures provide temporary effects (gastric balloon, Botox), while others offer longer-term results (ESG, AspireAssist). Dr. Lalezari will
discuss expected duration during your consultation.
Consult With Our Experts at Lalezari Surgical
Choosing the right procedural weight loss option is an important decision that requires careful consideration and professional guidance from a qualified specialist. Dr. Lalezari’s unique combination of surgical expertise and advanced endoscopic skills ensures that you receive the most appropriate treatment for your individual needs.
We invite you to schedule a consultation with Dr. Sepehr Lalezari to discuss your options and how our services can be tailored to meet your specific weight loss goals. During your consultation, you will benefit from:
- Personal evaluation by a fellowship-trained bariatric specialist
- Comprehensive discussion of all available treatment options
- Evidence-based recommendations tailored to your situation
- Access to the most advanced minimally invasive techniques
- Continuity of care with potential surgical options if needed
Experience the Difference with Lalezari Surgical
Step into a new phase of life with confidence and health under the expert care of Los Angeles’ leading bariatric specialist. Dr. Lalezari’s combination of Johns Hopkins training, extensive clinical experience, and commitment to patient-centered care provides the foundation for successful long-term weight loss.
Why Choose Dr. Lalezari for Non-Surgical Weight Loss:
- Fellowship-trained in minimally invasive bariatric surgery from Johns Hopkins
- Board-certified FACS with 8+ years of specialized experience
- Published researcher in advanced endoscopic techniques
- Los Angeles Magazine “Top Doctor” recognition (2021-2024)
- Comprehensive approach with all treatment options available
- State-of-the-art facilities in Downtown Los Angeles and Long Beach
Contact us today to learn more about our Procedural Weight Loss Services and how we can assist you in achieving your weight loss and health goals through expert minimally invasive care.
Dr. Sepehr Lalezari is a board-certified bariatric surgeon with fellowship training from Johns Hopkins Medicine. Individual results may vary. This information is for educational purposes and does not replace professional medical advice. Always consult with Dr. Lalezari or a qualified healthcare provider before starting any weight loss procedure.